Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients

Non-Coding RNAs in Primary Liver Cancer

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with poor prognosis and limited therapeutic options. Over the past few years, many studies have evaluated the role of non-coding RNAs (ncRNAs) in hepatocarcinogenesis and tumor progression. ncRNAs were shown to have diagnostic, prognostic, and therapeutic potential in HCC. In this manuscript, we review the latest major discover...

Chromosomal Abnormality in Men with Impaired Spermatogenesis

Chromosomal abnormality in patients with secondary amenorrhea.

BACKGROUND Secondary amenorrhea is a condition in which there is cessation of menses after at least one menstruation. It is a symptom of different diseases, such as hormonal disturbances which range from pituitary to ovarian origin, as well as chromosomal abnormalities. Knowledge of the distinct cause of secondary amenorrhea is of tremendous benefit for the management and monitoring of patients...

Mucinous and Non-Mucinous Adenocarcinoma in Colorectal Cancer Patients

Background: The oncologic behavior of mucinous adenocarcinoma (MA) of colorectal differs from non-mucinous adenocarcinoma (NMA). MA is more advanced at diagnosis and has a poorer prognosis than NMA. We aimed to evaluate prognostic factors and survival rate in patients with MA compared with NMA in Western Iran. Methods: During 2008-2015 in a retrospective study, 83 patients with CRC referred to...

Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.

OBJECTIVE Chronic viral hepatitis B and C cause liver fibrosis, leading to cirrhosis. Fibrosis assessment is essential to establish prognosis and treatment indication. We compared seven non-invasive tests, separately and in combination, in chronic hepatitis patients to detect early stages of fibrosis according to the Metavir score in liver biopsy. MATERIAL AND METHODS Galactose and methacetin...